Promega Benelux

✍️ [BLOG] 𝐂𝐚𝐧 𝐀𝐈 𝐑𝐞𝐩𝐥𝐚𝐜𝐞 𝐇𝐢𝐠𝐡-𝐓𝐡𝐫𝐨𝐮𝐠𝐡𝐩𝐮𝐭 𝐒𝐜𝐫𝐞𝐞𝐧𝐬 𝐟𝐨𝐫 𝐃𝐫𝐮𝐠 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐲? 🚧 A major limitation to HTS is the need to synthesize all compounds used in the screen—the compounds need to physically exist to be tested. 🤖 What if we could test compounds even before they are synthesized? Read the full story on Promega Connections blog https://bit.ly/3ya1pxL

📝 [PROMEGA NOTE] 𝐍𝐚𝐯𝐢𝐠𝐚𝐭𝐢𝐧𝐠 𝐈𝐧 𝐕𝐢𝐯𝐨 𝐁𝐢𝐨𝐥𝐮𝐦𝐢𝐧𝐞𝐬𝐜𝐞𝐧𝐜𝐞 𝐈𝐦𝐚𝐠𝐢𝐧𝐠: 𝐓𝐢𝐩𝐬 𝐟𝐨𝐫 𝐄𝐧𝐡𝐚𝐧𝐜𝐞𝐝 𝐒𝐮𝐜𝐜𝐞𝐬𝐬 𝐚𝐧𝐝 𝐄𝐟𝐟𝐢𝐜𝐢𝐞𝐧𝐜𝐲 🔬 Optical imaging is revolutionizing the way we understand complex biological processes. By using fluorescence and bioluminescence, researchers can now observe protein behaviors, chemical reactions, and cell interactions in real time, within living organisms. 🔦 Bioluminescent Imaging (BLI) doesn't require external light, making it ideal for deep tissue observation in small animals. BLI is particularly effective for studying disease progression, drug efficacy, and viral infections non-invasively, aligning with the ethical 3Rs of animal research: Replacement, Reduction, and Refinement. 👓 Learn more about the key factors for successful 𝘪𝘯 𝘷𝘪𝘷𝘰 BLI by visiting the Promega website https://bit.ly/3QD6WDp

🔎 [NEW] 𝐈𝐋-𝟐𝐑βγ 𝐁𝐢𝐨𝐚𝐬𝐬𝐚𝐲 Assess the Mechanism of Action of Cytokine Biologics Designed to Target the Intermediate Affinity IL-2Rβγ Receptor ✅Lacks CD25 expression ✅Prequalified according to ICH guidelines ✅96- and 384-well plate formats ✅No primary cell culture required ✅Supplied in convenient thaw-and-use format; also available in cell propagation model (CPM) format More information: https://bit.ly/4adVjJU

📝 [APPNOTE] 𝐀𝐮𝐭𝐨𝐦𝐚𝐭𝐞𝐝 𝐃𝐍𝐀 𝐏𝐮𝐫𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐂𝐀𝐑-𝐓 𝐂𝐞𝐥𝐥𝐬 🧪🧬 Dive into our application note where we detail how to purify DNA from CAR-T cells using the Maxwell® RSC Cultured Cells DNA Kit and the Maxwell® RSC Instrument. 👉 https://bit.ly/4dsiROe

🖼️ [POSTER] 𝐀 𝐋𝐮𝐦𝐢𝐭 𝐡𝐮𝐦𝐚𝐧 𝐈𝐋-𝟏𝟖 𝐚𝐬𝐬𝐚𝐲 𝐦𝐞𝐚𝐬𝐮𝐫𝐞𝐬 𝐚𝐜𝐭𝐢𝐯𝐞 𝐈𝐋-𝟏𝟖 𝐢𝐧 𝐜𝐞𝐥𝐥 𝐜𝐮𝐥𝐭𝐮𝐫𝐞 💥 Interleukin-18 (IL-18), a proinflammatory cytokine, was first identified for its role in interferon-γ (IFN- γ) expression. It is activated when cleaved by caspases and can then bind to IL-18 receptor complexes. Active IL-18 secretion is a primary output of inflammasome activation and is associated with a myriad of inflammatory related diseases. 💡Here we show that we have developed a Lumit® based tool utilizing the IL-18 binding protein (IL-18bp), a soluble decoy receptor that binds to active IL-18 with high affinity and blocks receptor activation. ⬇️ Download the poster https://bit.ly/3wy5ZVY

✍️ [BLOG] 𝐒𝐢𝐥𝐞𝐧𝐜𝐢𝐧𝐠 𝐭𝐡𝐞 𝐈𝐦𝐦𝐮𝐧𝐨𝐠𝐞𝐧𝐢𝐜𝐢𝐭𝐲 𝐨𝐟 𝐀𝐀𝐕 𝐕𝐞𝐜𝐭𝐨𝐫𝐬 💉🧬 Recombinant adeno-associated viral (AAV) vectors are an appealing delivery strategy for in vivo gene therapy but face a formidable challenge: avoiding detection by an ever-watchful immune system. 👓 Read more about how a recent study introduced a new approach to reduce the inherent immunogenicity of AAV vectors on Promega Connections blog 👉 https://bit.ly/4dl4lYv

📺 [WEBINAR] 𝐅𝐫𝐨𝐦 𝐂𝐥𝐚𝐬𝐬𝐫𝐨𝐨𝐦 𝐭𝐨 𝐂𝐫𝐢𝐦𝐞 𝐋𝐚𝐛: 𝐂𝐚𝐫𝐞𝐞𝐫 𝐆𝐮𝐢𝐝𝐚𝐧𝐜𝐞 𝐟𝐫𝐨𝐦 𝐃𝐍𝐀 𝐄𝐱𝐩𝐞𝐫𝐭𝐬 📅 Wednesday, May 8, 2024 🕔 5pm CEST 👨🏫 Dr. Michael Coble, Associate Professor and the Executive Director, Center for Human Identification at the University of North Texas Health Science Center 👩🏫 Nana Lamousé-Welch, DNA Specialist, Forensic Science Unit of the Bronx County District Attorney Office 👩🏫 Michelle Madrid, Senior Criminalist and the DNA Technical Leader, Los Angeles County Sheriff’s Department 👩🏫 Julie Sikorsky, Forensic Biology Manager, Palm Beach County Sheriff's Office 👨🏫 Jim Thomson, Scientific Knowledge Manager and the Science Lead for DNA, Eurofins Forensic Services 👩🏫 Rhonda Williams, Associate Professor, University of Central Oklahoma Join this exclusive online event where aspiring forensic scientists can connect directly with leading figures in the field of forensic DNA. This engaging forum encourages students and early-career professionals to seek advice, discuss challenges, and explore opportunities within the realm of forensic DNA analysis. 🎟️ Registration: https://bit.ly/3UrlBma

🚀 𝐘𝐨𝐮𝐫 𝐅𝐚𝐬𝐭 𝐓𝐫𝐚𝐜𝐤 𝐭𝐨 𝐂𝐞𝐥𝐥 𝐕𝐢𝐚𝐛𝐢𝐥𝐢𝐭𝐲 𝐑𝐞𝐬𝐮𝐥𝐭𝐬 ⏩📊 Discover the MyGlo™ Reagent Reader, featuring an easy, sample-to-result approach for CellTiter-Glo® Assays. No waiting. No hassle. Focus on your research and let #MyGlo handle the rest. Get the details here: https://lnkd.in/eT3SYX9G

❄️[LYOPHILISATION] 𝐑𝐞𝐚𝐝𝐲 𝐭𝐨 𝐞𝐧𝐡𝐚𝐧𝐜𝐞 𝐲𝐨𝐮𝐫 𝐏𝐂𝐑 𝐰𝐨𝐫𝐤𝐟𝐥𝐨𝐰𝐬 𝐰𝐢𝐭𝐡 𝐞𝐟𝐟𝐢𝐜𝐢𝐞𝐧𝐜𝐲 𝐚𝐧𝐝 𝐞𝐚𝐬𝐞? 🧬🧪 Partner with Promega to accelerate the development and production of a lyophilized PCR assay specific to your needs. With everything you need in a single bead, add your sample and amplify, streamlining the sample preparation process.    🔎 Explore the benefits of a Lyophilized PCR Assay customized for your needs: https://bit.ly/3WkMfjg 

[CONFERENCE] 𝐀𝐭𝐭𝐞𝐧𝐝𝐢𝐧𝐠 𝐄𝐂𝐂𝐌𝐈𝐃 𝐭𝐡𝐢𝐬 𝐲𝐞𝐚𝐫? Join our team of experts for discussions on how Promega can support your clinical diagnostics solution. Don't miss the chance to explore our products, ask questions, and see firsthand how we can help enhance your lab's capabilities. 📅 Date: April 25-28 📍 Location: Booth E27, ECCMID Conference We look forward to seeing you there and helping you achieve your scientific goals! #ECCMID #microbiology #clinicalresearchµ