High Throughput Screening with permeable membrane inserts
Relevance of air-liquid interface (ALI) cultures
Culturing cells in an air-liquid interface (ALI) is a popular method for generating a stable and functional airway model by mimicking a pseudostratified epithelium in vitro.
ALI cell cultures are widely used to study various processes associated with the lower respiratory tract, such as disease modeling, in vitro drug screening, cell-to-cell signaling, and studies of lung toxicity caused by air pollutants.
What are the advantages of air-lift culture testing?
ALI cultures are of great use for studying the biology of the airway epithelium and for research into airway diseases (e.g. COVID-19 research). Numerous studies have already been published in very prestigious journals such as Nature, The New England Journal of Medicine and other major medical journals, with more to come.
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