Geavanceerde 3D cell culture voor innovatief onderzoek en gerichte diagnostiek

“Using organ-on-chip as advanced tool to mimic human-like behaviors”

Organ-on-chip (OoC) systems are revolutionizing biomedical research by offering physiologically relevant models of human tissues. chiron has developed innovative platforms that integrate active mechanical stimulation to better replicate in vivo conditions. By mimicking dynamic forces such as strain, shear, and compression, chiron’s devices enhance cellular behavior, tissue maturation, and predictive modeling. This talk will highlight how chiron’s technologies enable more accurate disease modeling, drug testing, and regenerative studies. Integrating mechanical cues into OoC systems represents a critical step toward bridging the gap between in vitro models and human physiology for more reliable translational outcomes.

Spreker: Carlo Alberto Paggi, Universiteit Twente

“Live-Cell Imaging of 3D Cell Cultures: from High-Throughput to High-Resolution”

The integration of live-cell imaging with 3D cell culture systems such as organoids is transforming how we assess biological responses in a lab setting. In this talk, I will explore how different imaging strategies—from high-throughput widefield imaging to high-resolution confocal microscopy—can be used to monitor complex 3D models in real time. We’ll walk through the practical implementation of these technologies in automated lab workflows and highlight how they can be scaled to meet the needs of modern research labs, hospitals, and contract research settings. The focus will be on instrumentation, imaging pipelines, and strategies to ensure consistent data acquisition across large experiments. I will also touch on how image analysis tools, including AI-based approaches, can support data interpretation and improve reproducibility, without requiring complex infrastructure. This presentation aims to provide a practical and technology-focused overview of what it takes to bring advanced live-cell imaging into routine lab practice.

Spreker: Christophe Deben, Universiteit Antwerpen