Van labdier naar labmodel: proefdiervrije toekomst in het lab

De ontwikkeling van medicijnen, medische technologie en voedingsproducten draagt bij aan een betere gezondheid en een duurzamere samenleving. Maar de manier waarop we dit onderzoek uitvoeren, staat steeds vaker ter discussie. Traditionele methoden, zoals dierproeven, bieden lang niet altijd een betrouwbare vertaling naar de mens. Dat vraagt om een nieuwe benadering. In dit seminar verkennen we hoe innovatieve technologieën en proefdiervrije methoden bijdragen aan een effectiever en mensgerichter onderzoeksproces. Je ontdekt hoe wetenschap, industrie en beleid samenwerken aan oplossingen die niet alleen ethischer zijn, maar ook beter presteren. Denk vooruit, kijk verder en ontdek de kansen van een toekomst zonder dierproeven.

Please note: this seminar will be held in English.

Presentation 1: “The Centre for Animal-Free Biomedical Translation (CPBT, in Dutch: Centrum voor Proefdiervrije Biomedische Translatie): a knowledge centre for valorizing and disseminating animal-free innovations and expertise.”

The translation of biomedical knowledge to patients and users results in new medicines, medical technologies, and food products. This benefits our health, our environment, and economy. Animal testing is currently an important link in the biomedical development process, but it is increasingly under pressure. Often, animal tests are not a good model for human application. To continue improving the health of humans and animals, a radically different approach is needed: making the step to humans and animals faster and more effective, without relying on animal testing by default.

The new Centre for Animal-Free Biomedical Translation (CPBT, in Dutch: Centrum voor Proefdiervrije Biomedische Translatie) will shape this approach, creating new business opportunities around animal-free technologies and biomedical translation.

Speaker: Daniela Salvatori

Presentation 2: A new ERA in Safety Testing of Industrial Chemicals

This presentation showcases the transformative shift in regulatory toxicology for industrial chemicals driven by the rise of New Approach Methodologies (NAMs). As a leading Contract Research Organization (CRO), Charles River Laboratories (CRL) is committed to the safe and efficient development of pharmaceuticals and industrial chemicals. With the evolving regulatory landscape, NAMs are increasingly recognized as scientifically robust, ethically sound, and human-relevant alternative to traditional animal testing.

Current examples of standalone NAMs and integrated NAMs already in use at CRL for the safety testing of industrial chemicals will be presented. These methods have partially or fully replaced animal testing or enhance the safety testing of chemicals for several toxicity endpoints. However, still a lot of innovation, validation and regulatory acceptance is needed to come to an overall animal free test strategy. The practical contribution of Charles River to this ongoing process will be discussed.

Speaker: Walter Westerink, Charles River Laboratories

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